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KMID : 0617819950050010331
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Journal of Wonkwang Oriental Medicine
1995 Volume.5 No. 1 p.331 ~ p.349
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Effects of Manhwangbujaseshintang(麻黃附子細辛湯) on the Cardiovascular System in the Experimental Animals
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Abstract
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The present experiments were designed to investigate the effects of Mahwangbuja-seshintang on the cardiovascular system by using the methods of measurement of blood pressure, Mg^2+ -Ca^2+ -ATPase activity of cardiac endoplasmic reticulum and digital inflared thermograph imaging analizer.
In order to control the precise chemical and physical animal conditions, the experimental animals were supplied with calorie limited food.
The results obtained were summarized as follows:
1. Mahwangbujaseshintang water extract increased the blood pressure and heart beat rate in the anesthetic rabbits.
2. Mahwangbujaseshintang seemed like to stimulate autonomous sympathetic nerve α and β receptors.
3. Mahwangbujaseshintang demonstrated the antihistamine effect by contracting the capillary, and thus it decreased the body surface temperature.
4. Mahwangbujaseshintang increased the blood pressure and heartrate by contracting the body surface capillaries.
According to the above result´s Mahwangbujaseshintang water extract has the curative effect on the heart disease and blood flow.
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